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Phenotypes Associated with This Genotype
Genotype
MGI:6188641
Allelic
Composition		 Atp11atm1c(KOMP)Wtsi/Atp11atm1c(KOMP)Wtsi
Myf5tm3(cre)Sor/Myf5+
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp11atm1c(KOMP)Wtsi mutation (0 available); any Atp11a mutation (54 available)
Myf5tm3(cre)Sor mutation (1 available); any Myf5 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
muscle phenotype ( J:262981 )
N
• mice exhibit normal gross muscle morphology and function (grip strength and treadmill running tests)
abnormal myoblast differentiation ( J:262981 )
• isolated primary myoblasts form aberrantly enlarged syncytia upon differentiation
abnormal skeletal muscle regeneration ( J:262981 )
• abnormally fused myofibers following cardiotoxin-induced regeneration of the tibialis anterior muscle

cellular
abnormal myoblast differentiation ( J:262981 )
• isolated primary myoblasts form aberrantly enlarged syncytia upon differentiation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory