Phenotypes for App Klk7 MGI:6160918 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	App^tm3.1Tcs/App^tm3.1Tcs Klk7^{tm1(KOMP)Vlcg}/Klk7^{tm1(KOMP)Vlcg}
Genetic Background	involves: C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
App^tm3.1Tcs mutation (2 available); any App mutation (118 available)
Klk7^{tm1(KOMP)Vlcg} mutation (1 available); any Klk7 mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

amyloid beta deposits ( J:261970 )

• increased 5.6-fold compared with App^tm3.1Tcs homozygotes

homeostasis/metabolism

amyloid beta deposits ( J:261970 )

• increased 5.6-fold compared with App^tm3.1Tcs homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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