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Phenotypes Associated with This Genotype
Genotype
MGI:6160754
Allelic
Composition
Plp1tm1c(EUCOMM)Wtsi/Y
Neurod6tm1(cre)Kan/Neurod6+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neurod6tm1(cre)Kan mutation (0 available); any Neurod6 mutation (13 available)
Plp1tm1c(EUCOMM)Wtsi mutation (0 available); any Plp1 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• no APP+axonal spheroids, microgliosis, astrogliosis, or increase in T-lymphocytes are seen in the hippocampal fimbria at 26 weeks of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
NOT hereditary spastic paraplegia 2 DOID:0110773 OMIM:312920
J:245100


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory