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Phenotypes Associated with This Genotype
Genotype
MGI:6154152
Allelic
Composition
Tg(EIIa-cre)C5379Lmgd/?
Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic
Background
involves: 129/Sv * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(EIIa-cre)C5379Lmgd mutation (4 available)
Trip11tm1.2Psmi mutation (0 available); any Trip11 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular

craniofacial

digestive/alimentary system

growth/size/body

skeleton
• E15.5 chondrocytes have a swollen appearance, massive expansion of the endoplasmic rediculum, and disruption of the golgi apparatus
• assessment of the humeri at E15.5 finds delayed formation of the primary ossificatiion center

limbs/digits/tail

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
achondrogenesis type IA DOID:0080054 OMIM:200600
J:253969


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory