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Phenotypes Associated with This Genotype
Genotype
MGI:6151156
Allelic
Composition		 Atg7tm1Tchi/Atg7tm1Tchi
Cnot3tm1.1Kjkb/Cnot3tm1.1Kjkb
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cfTg(Myh6-cre/Esr1*)1Jmk
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cfTg(Myh6-cre/Esr1*)1Jmk mutation (5 available); any A1cf mutation (37 available)
Atg7tm1Tchi mutation (3 available); any Atg7 mutation (52 available)
Cnot3tm1.1Kjkb mutation (0 available); any Cnot3 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased cardiac muscle contractility ( J:260012 )
• as in mice with one copy of A1cfTg(Myh6-cre/Esr1*)1Jmk

muscle
decreased cardiac muscle contractility ( J:260012 )
• as in mice with one copy of A1cfTg(Myh6-cre/Esr1*)1Jmk

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory