Phenotypes Associated with This Genotype

Genotype
MGI:6151076

• Allelic Composition: Slc29a2^{Gt(OST207791)Lex}/Slc29a2^{Gt(OST207791)Lex}
• Genetic Background: involves: 129S5/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased susceptibility to injury ( J:203572 )

• mice are profoundly protected from acute lung injury (ALI) and ALI-associated alterations in gas exchange with longer survival and increased bronchoalveolar lavage fluid adenosine levels and reduced IL6 levels in lung tissues compared with wild-type mice

immune system

decreased interleukin-6 secretion ( J:203572 )

• in the lungs of mice subjected to acute lung injury

hematopoietic system

hematopoietic system phenotype ( J:244602 )

N • adenosine uptake in erythrocytes is normal