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Phenotypes Associated with This Genotype
Genotype
MGI:6120562
Allelic
Composition
Gt(ROSA)26Sortm1.1(DUX4*)Plj/Gt(ROSA)26Sor+
Tg(ACTA1-cre)79Jme/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1.1(DUX4*)Plj mutation (1 available); any Gt(ROSA)26Sor mutation (1243 available)
Tg(ACTA1-cre)79Jme mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
• pups are stillborn and small
• pups develop until almost full term (E19.5)

limbs/digits/tail
• E16.5 embryos exhibit deformed limbs

growth/size/body
• observed in E16.5 embryos

nervous system
• E16.5 embryos exhibit aberrant spinal columns

skeleton
• E16.5 embryos exhibit underdeveloped rib cages

embryo
• observed in E16.5 embryos


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory