Phenotypes Associated with This Genotype

Genotype
MGI:6120559

• Allelic Composition: Gt(ROSA)26Sor^{tm1.1(DUX4*)Plj}/Gt(ROSA)26Sor⁺
• Genetic Background: B6(Cg)-Gt(ROSA)26Sor^{tm1.1(DUX4*)Plj}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:256652 )

• adult size is slightly reduced

• male mice are 14% smaller than controls by 20 weeks of age

• female mice are 11% smaller than controls by 20 weeks of age

postnatal growth retardation ( J:256652 )

• males exhibit slower growth after 8 weeks of age

• females exhibit slower growth after 12 weeks of age

immune system

enlarged lymph nodes ( J:256652 )

• swollen subiliac lymph nodes

enlarged popliteal lymph nodes ( J:256652 )

integument

alopecia ( J:256652 )

• mild alopecia

• phenotype is more severe in females than males

muscle

muscle phenotype ( J:256652 )

N • mice exhibit no overt myopathy