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Phenotypes Associated with This Genotype
Genotype
MGI:6117715
Allelic
Composition
Cemiptm1.1Tac/Cemiptm1.1Tac
Tg(Dhh-cre)1Mejr/0
Genetic
Background
involves: C57BL/6NTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cemiptm1.1Tac mutation (0 available); any Cemip mutation (70 available)
Tg(Dhh-cre)1Mejr mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• following nerve axotomy or sciatic nerve crush, mice exhibit reduced myelin degradation and increases remyelination compared with wild-type mice
• however, sciatic function index and Von Frey threshold are normal after nerve crush
• transient acceleration of postnatal myelination
• however, adult myelination is normal

homeostasis/metabolism
• following nerve axotomy or sciatic nerve crush, mice exhibit reduced myelin degradation and increases remyelination compared with wild-type mice
• however, sciatic function index and Von Frey threshold are normal after nerve crush


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory