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Phenotypes Associated with This Genotype
Genotype
MGI:6117709
Allelic
Composition		 Smoc2tm1.1(KOMP)Vlcg/Smoc2tm1.1(KOMP)Vlcg
Genetic
Background		 involves: C57BL/6J * C57BL/6NTac * CBA
Cell Lines 16694B-G5
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smoc2tm1.1(KOMP)Vlcg mutation (1 available); any Smoc2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased susceptibility to injury ( J:244221 )
• mice subjected to unilateral ureteral obstruction or treated with FA exhibit protection from kidney fibrosis with reduced interstitial myofibroblast accumulation compared with wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory