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Phenotypes Associated with This Genotype
Genotype
MGI:6117338
Allelic
Composition		 Pcdh19tm1Tac/Pcdh19tm1Tac
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcdh19tm1Tac mutation (0 available); any Pcdh19 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:256961 , J:255320 )
N
• despite expression patterns, brain structure appears normal and cells are located in the expected locations (J:256961)
• electrocorticograms are indistinguishable from wild-type controls at P42 (J:255320)
abnormal neuronal migration ( J:256961 )
• neurons in cultured neurospheres show increased migration

behavior/neurological
behavior/neurological phenotype ( J:256961 )
N
• no spontaneous seizures detected after weaning

cellular
abnormal neuronal migration ( J:256961 )
• neurons in cultured neurospheres show increased migration

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory