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Phenotypes Associated with This Genotype
Genotype
MGI:6114670
Allelic
Composition		 Pik3ap1m2Btlr/Pik3ap1m2Btlr
Genetic
Background		 C57BL/6J-Pik3ap1m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3ap1m2Btlr mutation (0 available); any Pik3ap1 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B-1a cell number ( J:255271 )
• in the peripheral blood
increased B-1b cell number ( J:255271 )
• in the peripheral blood
increased IgM level ( J:255271 )
• diminished T-independent antibody (IgM) response to NP-Ficoll
impaired humoral immune response ( J:255271 )
• diminished T-independent antibody (IgM) response to NP-Ficoll

hematopoietic system
decreased B-1a cell number ( J:255271 )
• in the peripheral blood
increased B-1b cell number ( J:255271 )
• in the peripheral blood
increased IgM level ( J:255271 )
• diminished T-independent antibody (IgM) response to NP-Ficoll

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory