About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6111404
Allelic
Composition
Tcte1tm1a(KOMP)Wtsi/Tcte1tm1a(KOMP)Wtsi
Genetic
Background
C57BL/6N-Tcte1tm1a(KOMP)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcte1tm1a(KOMP)Wtsi mutation (2 available); any Tcte1 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• female fertility (J:243766)
N
• testis weight (J:243766)
• sperm number (J:243766)
• spermatogenesis (J:243766)
• acrosome morphology (J:243766)
• tubules full of spermatozoa in caput epididymis (J:243766)
• tubules full of spermatozoa in cauda epididymis (J:243766)
• sperm axoneme morphology (J:243766)
• spermatozoa morphology
• significantly lower ATP levels in spermatozoa
• limited flagellar beating range
• unbalanced flagellar beating
• decreased forwardly motile spermatozoa using a Computer Assisted Sperm Analyzer (CASA)
• no pups born from mating homozygous males to wildtype or heterozygous females

cellular
• spermatozoa morphology
• significantly lower ATP levels in spermatozoa
• limited flagellar beating range
• unbalanced flagellar beating
• decreased forwardly motile spermatozoa using a Computer Assisted Sperm Analyzer (CASA)

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
male infertility DOID:12336 J:243766


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/24/2020
MGI 6.15
The Jackson Laboratory