Phenotypes Associated with This Genotype

Genotype
MGI:6110830

• Allelic Composition: Osr2^tm2(cre)Jian/Osr2⁺; Tg(CAG-Bmp4,-EGFP)1Ypc/0
• Genetic Background: involves: 129S1/Sv * C57BL/6J * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

palatal shelves fail to meet at midline ( J:214763 )

• at the anterior level, the palatal shelves elevate but fail to contact

• however, origin of palatal shelves form the maxillary processes remains unaltered

palatal shelf fusion with tongue or mandible ( J:214763 )

• at the posterior level, the palatal shelves remain at the vertical orientation, showing abnormal fusion with the mandible

cleft palate ( J:214763 )

digestive/alimentary system

palatal shelves fail to meet at midline ( J:214763 )

• at the anterior level, the palatal shelves elevate but fail to contact

• however, origin of palatal shelves form the maxillary processes remains unaltered

palatal shelf fusion with tongue or mandible ( J:214763 )

• at the posterior level, the palatal shelves remain at the vertical orientation, showing abnormal fusion with the mandible

cleft palate ( J:214763 )

growth/size/body

palatal shelves fail to meet at midline ( J:214763 )

• at the anterior level, the palatal shelves elevate but fail to contact

• however, origin of palatal shelves form the maxillary processes remains unaltered

palatal shelf fusion with tongue or mandible ( J:214763 )

• at the posterior level, the palatal shelves remain at the vertical orientation, showing abnormal fusion with the mandible

cleft palate ( J:214763 )