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Phenotypes Associated with This Genotype
Genotype
MGI:6107637
Allelic
Composition		 MmachcGt(AZ0348)Wtsi/MmachcGt(AZ0348)Wtsi
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * CD-1
Cell Lines AZ0348
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MmachcGt(AZ0348)Wtsi mutation (0 available); any Mmachc mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:212387 )
• expected Mendelian ratio with heterozygous crosses at E3.5
• no homozygous KOs post-implantation

reproductive system
impaired embryo implantation ( J:212387 )
• no homozygous KOs post-implantation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory