adipose tissue
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• pale axillary and cervical brown adipose tissue depots
• however, tissue mass is not altered
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• in the interscapular brown adipose tissue of mice older than 6 months
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• in the interscapular brown adipose tissue of mice older than 6 months
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• whitening in mice older than 6 months with increased size of the tissue, a switch from multilocular to unilocular morphology, and increased lipid content
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• in unstimulated interscapular brown adipose tissue
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• whitening in mice older than 6 months with increased size of the tissue, a switch from multilocular to unilocular morphology, and increased lipid content
• 3 week old mice fed a high-fat diet exhibit loss of normal brown adipocyte morphology unlike wild-type mice
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• in mice older than 6 months
• however, juvenile mice exhibit normal sized brown adipose tissue depots
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• precipitous drop in body temperature following exposure to cold
• however, diet-induced thermogenesis is normal
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• reduced basal in interscapular brown adipose tissue
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homeostasis/metabolism
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• precipitous drop in body temperature following exposure to cold
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growth/size/body
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• at all ages
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cellular
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• in unstimulated interscapular brown adipose tissue
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• reduced basal in interscapular brown adipose tissue
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• with poorly organized cristae in unstimulated interscapular brown adipose tissue
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