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Phenotypes Associated with This Genotype
Genotype
MGI:6106902
Allelic
Composition		 Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sortm1(cre/ERT2)Tyj
Nus1tm1.1Qrm/Nus1tm1.1Qrm
Genetic
Background		 involves: 129 * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT2)Tyj mutation (7 available); any Gt(ROSA)26Sor mutation (1098 available)
Nus1tm1.1Qrm mutation (0 available); any Nus1 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal lipid homeostasis ( J:243753 )
• induction of hepatic lipogenesis when fed Western diet
increased liver free fatty acids level ( J:243753 )
• when fed Western diet
increased liver triglyceride level ( J:243753 )
• when fed Western diet

liver/biliary system
increased liver free fatty acids level ( J:243753 )
• when fed Western diet
increased liver triglyceride level ( J:243753 )
• when fed Western diet
hepatic steatosis ( J:243753 )
• when fed Western diet

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory