Phenotypes for Prf1 Yaa MGI:6105950 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Prf1^tm1Sdz/Prf1^tm1Sdz X/Yaa
Genetic Background	BXSB.B6-Prf1^tm1Sdz/Dcr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prf1^tm1Sdz mutation (17 available); any Prf1 mutation (54 available)
Yaa mutation (23 available); any Yaa mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

autoimmune response ( J:179430 )

• death as a result of the Yaa-induced SLE-like autoimmunity is slightly increased in the early segment of the mortality curve relative to Yaa-bearing controls without the null allele

mortality/aging

premature death ( J:179430 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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