Analysis Tools
vision/eye
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• the enlarged extracellular spaces and disrupted fiber-to-fiber contacts in the fiber cells of the lens core of crystallin gamma b mutants is rescued in these double homozygotes
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• while the alpha 3 connexin knockin rescues the dense nuclear cataract otherwise caused by the crystallin gamma b mutation, a very mild cortical opacity with a ring-like defect is still found in these double homozygotes and the lenses have much lower light scattering at 21 days of age compared with un-rescued crystallin gamma b mutants, but is still 6% higher than wild-type controls
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