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Phenotypes Associated with This Genotype
Genotype
MGI:6098745
Allelic
Composition
Bpifb1tm1a(KOMP)Wtsi/Bpifb1tm1a(KOMP)Wtsi
Genetic
Background
C57BL/6N-Bpifb1tm1a(KOMP)Wtsi
Cell Lines EPD0704_3_A09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bpifb1tm1a(KOMP)Wtsi mutation (1 available); any Bpifb1 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• Background Sensitivity: depletion of homozygotes in the third generation
• however, this effect is not observed in subsequent generations

respiratory system
• 3-fold increased MUC5B in bronchoalveolar fluid of mice under baseline conditions, which persists after sensitization and challenge
• however, MUC5A production is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory