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Phenotypes Associated with This Genotype
Genotype
MGI:5912374
Allelic
Composition		 Lrfn3tm1(KOMP)Vlcg/Lrfn3tm1(KOMP)Vlcg
Lrfn4tm1(KOMP)Vlcg/Lrfn4tm1(KOMP)Vlcg
Genetic
Background		 involves: C57BL/6J * C57BL/6NTac
Cell Lines 15252A-A12, 10115A-A9
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrfn3tm1(KOMP)Vlcg mutation (1 available); any Lrfn3 mutation (24 available)
Lrfn4tm1(KOMP)Vlcg mutation (1 available); any Lrfn4 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:241274 )
N
• neurons exhibit normal miniature excitatory postsynaptic current frequency, amplitude and synapse numbers
abnormal synapse morphology ( J:241274 )
• increased inhibitory synapse density

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory