Phenotypes Associated with This Genotype

Genotype
MGI:5912262

• Allelic Composition: dft/dft
• Genetic Background: B6;FVB-dft/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

short tail ( J:243755 )

• variability in tail length, with the most severely impacted homozygote having only a short stub of a tail

kinked tail ( J:243755 )

reproductive system

decreased litter size ( J:243755 )

• intercrosses of homozygotes with heterozygotes yielded an average litter size of only 4 and intercrosses of heterozygotes yielded an average litter size of approximately 5

mortality/aging

prenatal lethality, incomplete penetrance ( J:243755 )

• intercrossing heterozygotes with homozygotes yielded only 22.7% mutants instead of the expected 50% and intercrossing heterozygotes yielded only 13.3% mutants instead of the expected 25%, which combined with the lower than normal litter size indicates some loss of homozygotes to prenatal lethality