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Phenotypes Associated with This Genotype
Genotype
MGI:5911876
Allelic
Composition
Sgcdtm1Mcn/Sgcdtm1Mcn
Genetic
Background
B6.129-Sgcdtm1Mcn/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sgcdtm1Mcn mutation (1 available); any Sgcd mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular

cardiovascular system
• cardiac cell degeneration
• 14 week old mice develop signs of mild cardiomyopathy with patchy areas of fibrosis and necrosis
• heart function is reduced with mice showing reduced fractional shortening

muscle
• cardiac cell degeneration
• 14 week old mice develop signs of mild cardiomyopathy with patchy areas of fibrosis and necrosis
• heart function is reduced with mice showing reduced fractional shortening

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
dilated cardiomyopathy 1L DOID:0110436 OMIM:606685
J:234761


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory