hematopoietic system
|
• following exposure to 5-fluorouracil
|
|
• in untreated mice and following exposure to 5-fluorouracil
|
|
• prolonged following exposure to 5-fluorouracil
|
homeostasis/metabolism
| N |
• mice exhibit normal plasma homocysteine levels
|
|
• half as much total folate in the bone marrow as in wild-type mice
• however, sub-species levels are normal
|
cardiovascular system
|
• impaired endothelium-dependent in the aorta
• however, mice exhibit normal relaxation induced by the NO donor DEANO
|
immune system
|
• following exposure to 5-fluorouracil
|
muscle
|
• impaired endothelium-dependent in the aorta
• however, mice exhibit normal relaxation induced by the NO donor DEANO
|
growth/size/body
|
• following exposure to 5-fluorouracil
|


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