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Phenotypes Associated with This Genotype
Genotype
MGI:5904596
Allelic
Composition		 Trem2em2Bwef/Trem2+
Genetic
Background		 involves: C57BL/6J * DBA/2J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trem2em2Bwef mutation (0 available); any Trem2 mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased macrophage cell number ( J:242126 )
• fewer macrophages are produced from bone marrow cells stimulated with colony-stimulating factor

immune system
decreased macrophage cell number ( J:242126 )
• fewer macrophages are produced from bone marrow cells stimulated with colony-stimulating factor

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory