Phenotypes Associated with This Genotype

Genotype
MGI:5898024

• Allelic Composition: Agbl5^em1Zfa/Agbl5^em1Zfa
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to Herpesvirales infection ( J:231311 )

• following herpes simplex virus (HSV) infection, mice exhibit increased mortality and viral load with decreased IFN alpha and beta compared with wild-type mice

increased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:231311 )

• following herpes simplex virus (HSV) infection, mice exhibit increased mortality compared with wild-type mice

increased susceptibility to Poxviridae infection ( J:231311 )

• following vaccinia virus (VACV) infection, mice exhibit increased mortality and viral load with decreased IFN alpha and beta compared with wild-type mice

increased susceptibility to Poxviridae infection induced morbidity/mortality ( J:231311 )

• following vaccinia virus (VACV) infection, mice exhibit increased mortality compared with wild-type mice

mortality/aging

increased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:231311 )

• following herpes simplex virus (HSV) infection, mice exhibit increased mortality compared with wild-type mice

increased susceptibility to Poxviridae infection induced morbidity/mortality ( J:231311 )

• following vaccinia virus (VACV) infection, mice exhibit increased mortality compared with wild-type mice