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Phenotypes Associated with This Genotype
Genotype
MGI:5897867
Allelic
Composition		 Fan1tm1d(KOMP)Wtsi/Fan1tm1d(KOMP)Wtsi
Mus81tm1Chmg/Mus81tm1Chmg
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6N * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fan1tm1d(KOMP)Wtsi mutation (0 available); any Fan1 mutation (99 available)
Mus81tm1Chmg mutation (0 available); any Mus81 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased physiological sensitivity to xenobiotic ( J:232402 )
• MEFs are as sensitive to mitomycin C as cells from mice homozygous for Fan1 alone

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory