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Phenotypes Associated with This Genotype
Genotype
MGI:5897676
Allelic
Composition		 Sox10Dom/Sox10+
Genetic
Background		 involves: C3HeB/FeJLe * C57BL/6JLe
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox10Dom mutation (1 available); any Sox10 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal neural crest cell migration ( J:45117 )
• delayed migration at E10.5 and E11.5

nervous system
abnormal enteric neuron morphology ( J:45117 )
• delayed enteric neuron colonization of the entire gut at E11

embryo
abnormal neural crest cell migration ( J:45117 )
• delayed migration at E10.5 and E11.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory