Phenotypes Associated with This Genotype

Genotype
MGI:5897351

• Allelic Composition: Tg(Myh6-Atp1a2)1Jmol/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal myocardial fiber morphology ( J:223625 )

• following transverse aortic constriction to induce pressure overload hypertrophy

abnormal heart ventricles weight ( J:223625 )

• following transverse aortic constriction to induce pressure overload hypertrophy

decreased response of heart to induced stress ( J:223625 )

• following transverse aortic constriction to induce pressure overload hypertrophy, mice exhibit reduced ventricular weight with reduced myocyte cross-sectional area and reduced lung weight compared with wild-type mice

homeostasis/metabolism

decreased response of heart to induced stress ( J:223625 )

• following transverse aortic constriction to induce pressure overload hypertrophy, mice exhibit reduced ventricular weight with reduced myocyte cross-sectional area and reduced lung weight compared with wild-type mice

muscle

abnormal myocardial fiber morphology ( J:223625 )

• following transverse aortic constriction to induce pressure overload hypertrophy

respiratory system

decreased lung weight ( J:223625 )

• following transverse aortic constriction to induce pressure overload hypertrophy