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Phenotypes Associated with This Genotype
Genotype
MGI:5897114
Allelic
Composition		 Fnip1tm1.1Baba/Fnip1tm1.1Baba
Fnip2tm1.1Lss/Fnip2tm1.1Lss
Tg(Cdh16-cre)91Igr/0
Genetic
Background		 involves: C57BL/6 * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fnip1tm1.1Baba mutation (0 available); any Fnip1 mutation (60 available)
Fnip2tm1.1Lss mutation (0 available); any Fnip2 mutation (60 available)
Tg(Cdh16-cre)91Igr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:220672 )
• survival time is about 3 weeks

renal/urinary system

cellular
abnormal mitochondrial physiology ( J:220672 )
• increased respiratory capacity and mitochondrial surface area indicating increased mitochondrial biogenesis

growth/size/body
polycystic kidney ( J:220672 )
enlarged kidney ( J:220672 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory