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Phenotypes Associated with This Genotype
Genotype
MGI:5896743
Allelic
Composition		 Gli3Xt-J/Gli3+
Spoptm1c(KOMP)Mbp/Spoptm1c(KOMP)Mbp
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: C3H/HeJ * C57BL/6J * C57BL/6N * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli3Xt-J mutation (3 available); any Gli3 mutation (80 available)
Spoptm1c(KOMP)Mbp mutation (0 available); any Spop mutation (35 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
skeleton phenotype ( J:239074 )
N
• length of metacarpals, metatarsals and phalanges are similar to controls and significantly longer than in conditional mice wild-type for Gli3
• near wild-type levels of bone density and thickness of bone spicules are restored in the femur

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory