Phenotypes Associated with This Genotype

Genotype
MGI:5896626

• Allelic Composition: Slc13a4^{tm1c(EUCOMM)Wtsi}/Slc13a4^{tm1d(EUCOMM)Wtsi}; Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:239786 )

N • with paternal inheritance of the cre transgene mice are viable

lethality throughout fetal growth and development, complete penetrance ( J:239786 )

• with maternal inheritance of the cre transgene these mice phenocopy mice homozygous for Slc13a4 ^{tm1a(EUCOMM)Wtsi}

embryo

embryo phenotype ( J:239786 )

N • with paternal inheritance of the cre transgene restricting cre expression to the embryo and not the extraembryonic tissues, placental transport of sulfate is similar to controls and embryos resemble controls