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Phenotypes Associated with This Genotype
Genotype
MGI:5828493
Allelic
Composition		 Tg(Camk2a-tTA)1Mmay/0
Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
Tg(tetO-MAPT*A152T)L1Lms/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Camk2a-tTA)1Mmay mutation (8 available)
Tg(tetO-MAPT*A152T)L1Lms mutation (1 available)
Zbtb20Tg(PDGFB-APPSwInd)20Lms mutation (1 available); any Zbtb20 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality at weaning ( J:233816 )
• surviving mice die shortly after weaning
preweaning lethality, incomplete penetrance ( J:233816 )
• fewer than the expected numbers (only 2 of 141) of mice were obtained, indicating early lethality

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory