Phenotypes for Nodal MGI:5827600 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nodal^tm2Rob/Nodal^tm2Rob
Genetic Background	129S(Cg)-Nodal^tm2Rob

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nodal^tm2Rob mutation (0 available); any Nodal mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal mesendoderm development ( J:238567 )

• axial mesendoderm does not develop

rostral body truncation ( J:238567 )

• embryos show a spectrum of defects, ranging from no phenotype through a moderate anterior truncation in which some of the midbrain is retain to a severe anterior truncation in which all forebrain and midbrain tissue is absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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