Phenotypes Associated with This Genotype

Genotype
MGI:5825317

• Allelic Composition: Ufl1^{tm1a(EUCOMM)Wtsi}/Ufl1^{tm1a(EUCOMM)Wtsi}
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0169_3_F12

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:238253 )

• some mice die as early as E10.5

• no mice are present at E12.5

hematopoietic system

anemia ( J:238253 )

• at E11.5

decreased erythroid progenitor cell number ( J:238253 )

• reduced CFU-E and BFU-E from E11.5 fetal livers

increased nucleated erythrocyte cell number ( J:238253 )

• at E11.5

growth/size/body

decreased embryo size ( J:238253 )

• at E11.5

liver/biliary system

small liver ( J:238253 )

• at E11.5

embryo

decreased embryo size ( J:238253 )

• at E11.5