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Phenotypes Associated with This Genotype
Genotype
MGI:5819197
Allelic
Composition		 Cep63Gt(EUCE0251h11)Hmgu/Cep63Gt(EUCE0251h11)Hmgu
Chek2tm1Mak/Chek2tm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cep63Gt(EUCE0251h11)Hmgu mutation (0 available); any Cep63 mutation (42 available)
Chek2tm1Mak mutation (1 available); any Chek2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
thin cerebral cortex ( J:224364 )
• significant reduction in cortical thickness, as determined in motor and visual cortex sections at P60, similar to that in single Cep63Gt(EUCE0251h11)Hmgu homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory