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Phenotypes Associated with This Genotype
Genotype
MGI:5818861
Allelic
Composition
A/?
Tyrem8Ove/Tyrem8Ove
Genetic
Background
involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (80 available); any a mutation (468 available)
Tyrem8Ove mutation (1 available); any Tyr mutation (382 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the ears of mice homozygous for this Tyr promoter deletion on an agouti background appear gray
• the fur of these mice appears light tan
• tails of these mice exhibit minimal pigmentation

craniofacial
• the ears of mice homozygous for this Tyr promoter deletion on an agouti background appear gray

limbs/digits/tail
• tails of these mice exhibit minimal pigmentation

growth/size/body
• the ears of mice homozygous for this Tyr promoter deletion on an agouti background appear gray

hearing/vestibular/ear
• the ears of mice homozygous for this Tyr promoter deletion on an agouti background appear gray

pigmentation
• the ears of mice homozygous for this Tyr promoter deletion on an agouti background appear gray
• the fur of these mice appears light tan
• tails of these mice exhibit minimal pigmentation

vision/eye


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory