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Phenotypes Associated with This Genotype
Genotype
MGI:5818667
Allelic
Composition		 Gria4spkw1/Gria4spkw1
Pcnx2em5Frk/Pcnx2em5Frk
Genetic
Background		 C3Fe.C3-Pcnx2em5Frk Gria4spkw1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria4spkw1 mutation (3 available); any Gria4 mutation (71 available)
Pcnx2em5Frk mutation (0 available); any Pcnx2 mutation (130 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal spike wave discharge ( J:228536 )
• incidence and length of spike wave discharges is decreased as compared to mice homozygous for Gria4spkw1 alone
• incidence and length of spike wave discharges is slightly decreased as compared to C3H/HeJ

nervous system
abnormal spike wave discharge ( J:228536 )
• incidence and length of spike wave discharges is decreased as compared to mice homozygous for Gria4spkw1 alone
• incidence and length of spike wave discharges is slightly decreased as compared to C3H/HeJ

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory