Phenotypes Associated with This Genotype

Genotype
MGI:5810132

• Allelic Composition: Srrm4^{tm1b(EUCOMM)Wtsi}/Srrm4⁺
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon guidance ( J:221584 )

• at E18.5, the corpus callosum is not grossly misshapen but contains ectopic ventrally projecting bundles

abnormal stratification in cerebral cortex ( J:221584 )

• at E18.5, cortical layer VI is enlarged and the number of deep, early-born Tbr1+ neurons in layer VI is increased, though to a lesser extent than in homozygotes

• preplate definition is altered

cellular

abnormal axon guidance ( J:221584 )

• at E18.5, the corpus callosum is not grossly misshapen but contains ectopic ventrally projecting bundles