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Phenotypes Associated with This Genotype
Genotype
MGI:5807349
Allelic
Composition
Chd7tm1.1Dmm/Chd7tm1.1Dmm
Tg(Pax6-cre,GFP)1Pgr/0
Genetic
Background
involves: 129S6/SvEvTac * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7tm1.1Dmm mutation (1 available); any Chd7 mutation (133 available)
Tg(Pax6-cre,GFP)1Pgr mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• lenses at E12.5 are smaller but appear normal
• however, mice show well-formed eye structures at E12.5, the presence of optic cup and stalk, and the emerging retinal and pigmented epithelial layers from the optic cup appear normal and mice do not exhibit coloboma


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory