Phenotypes Associated with This Genotype

Genotype
MGI:5807128

• Allelic Composition: Cd8a^m2Btlr/Cd8a^m2Btlr
• Genetic Background: C57BL/6J-Cd8a^m2Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased CD8-positive, alpha-beta memory T cell proliferation ( J:236677 )

• effector memory CD8+ T cells in CD8+ T cells

abnormal CD8-positive, alpha-beta T cell physiology ( J:236677 )

• increase in the CD4+ to CD8+ T cell ratio caused by reduced frequencies of CD8+ T cells and CD8+ T cells in CD3+ T cells, and increased and naive CD8+ T cells in CD8+ T cells

cellular

increased CD8-positive, alpha-beta memory T cell proliferation ( J:236677 )

• effector memory CD8+ T cells in CD8+ T cells

hematopoietic system

increased CD8-positive, alpha-beta memory T cell proliferation ( J:236677 )

• effector memory CD8+ T cells in CD8+ T cells

abnormal CD8-positive, alpha-beta T cell physiology ( J:236677 )

• increase in the CD4+ to CD8+ T cell ratio caused by reduced frequencies of CD8+ T cells and CD8+ T cells in CD3+ T cells, and increased and naive CD8+ T cells in CD8+ T cells