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Phenotypes Associated with This Genotype
Genotype
MGI:5800512
Allelic
Composition
Tg(Prnp-PFN1*C71G)22Zxu/0
Tg(Thy1-PFN1*C71G)67Zxu/0
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Prnp-PFN1*C71G)22Zxu mutation (1 available)
Tg(Thy1-PFN1*C71G)67Zxu mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• paralysis at 305 +/-34 days

mortality/aging
• due to paralysis

muscle
• muscle weakness beginning at an average age of 295 days


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory