Phenotypes Associated with This Genotype

Genotype
MGI:5797886

• Allelic Composition: Trappc9^{tm1a(EUCOMM)Wtsi}/Trappc9^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Trappc9^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0596_4_E10

Data Sources

IMPC Data for Trappc9

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - WTSI

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - WTSI

cardiovascular system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

absent ductus venosus valve ( J:239583 )

DMDD

dual inferior vena cava ( J:239583 )

DMDD

abnormal inferior vena cava valve morphology ( J:239583 )

DMDD

abnormal interatrial septum morphology ( J:239583 )

DMDD

abnormal pulmonary valve cusp morphology ( J:239583 )

DMDD

hemorrhage ( J:239583 )

DMDD

internal hemorrhage ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal cystic duct morphology ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - WTSI

thoracoschisis ( J:239583 )

DMDD

heterochrony ( J:239583 )

DMDD

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - WTSI

increased red blood cell distribution width ( J:211773 )

♀

IMPC - WTSI

increased mean platelet volume ( J:211773 )

IMPC - WTSI

increased CD11b-high dendritic cell number ( J:211773 )

IMPC - WTSI

decreased CD11b-low dendritic cell number ( J:211773 )

IMPC - WTSI

decreased KLRG1-positive NK cell number ( J:211773 )

IMPC - WTSI

decreased gamma-delta T cell number ( J:211773 )

♀

IMPC - WTSI

increased monocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C high monocyte number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C low monocyte number ( J:211773 )

♀

IMPC - WTSI

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - WTSI

increased circulating insulin level ( J:211773 )

♀

IMPC - WTSI

increased circulating sodium level ( J:211773 )

♂

IMPC - WTSI

impaired glucose tolerance ( J:211773 )

♀

IMPC - WTSI

immune system

increased CD11b-high dendritic cell number ( J:211773 )

IMPC - WTSI

decreased CD11b-low dendritic cell number ( J:211773 )

IMPC - WTSI

decreased KLRG1-positive NK cell number ( J:211773 )

IMPC - WTSI

decreased gamma-delta T cell number ( J:211773 )

♀

IMPC - WTSI

increased monocyte cell number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C high monocyte number ( J:211773 )

♀

IMPC - WTSI

increased Ly6C low monocyte number ( J:211773 )

♀

IMPC - WTSI

blood in lymph vessels ( J:239583 )

DMDD

integument

abnormal vibrissa morphology ( J:211773 )

♂

IMPC - WTSI

liver/biliary system

abnormal cystic duct morphology ( J:239583 )

DMDD

muscle

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

nervous system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

abnormal lateral ventricle morphology ( J:239583 )

DMDD

abnormal dorsal root ganglion morphology ( J:239583 )

DMDD

renal/urinary system

abnormal urethra morphology ( J:239583 )

DMDD

respiratory system

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

skeleton

decreased bone mineral content ( J:211773 )

♀

IMPC - WTSI