Phenotypes Associated with This Genotype

Genotype
MGI:5797861

• Allelic Composition: Tfap4^{tm1.1(KOMP)Vlcg}/Tfap4^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Tfap4^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 15795A-B8

Data Sources

IMPC Data for Tfap4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - UCD

enlarged heart ( J:211773 )

IMPC - UCD

decreased heart rate ( J:211773 )

♀

IMPC - UCD

prolonged RR interval ( J:211773 )

♀

IMPC - UCD

endocrine/exocrine glands

decreased thymus weight ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

IMPC - UCD

increased lean body mass ( J:211773 )

♂

IMPC - UCD

hematopoietic system

decreased thymus weight ( J:211773 )

♂

IMPC - UCD

increased mean corpuscular volume ( J:211773 )

IMPC - UCD

increased red blood cell distribution width ( J:211773 )

IMPC - UCD

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - UCD

immune system

decreased thymus weight ( J:211773 )

♂

IMPC - UCD

liver/biliary system

decreased liver weight ( J:211773 )

♂

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - UCD

skeleton

abnormal lumbar vertebrae morphology ( J:211773 )

IMPC - UCD

abnormal sacral vertebrae morphology ( J:211773 )

IMPC - UCD