Phenotypes Associated with This Genotype

Genotype
MGI:5796004

• Allelic Composition: Rnf112^{tm1(KOMP)Vlcg}/Rnf112^{tm1(KOMP)Vlcg}
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal reproductive system physiology ( J:232515 )

• some breeding inconsistency

nervous system

decreased brain size ( J:232515 )

• in some mice

decreased dendritic spine number ( J:232515 )

• fewer dendritic spines in vivo

abnormal miniature excitatory postsynaptic currents ( J:232515 )

• decreased frequency

• however, amplitude and mini decay are normal

decreased paired-pulse facilitation ( J:232515 )