Phenotypes Associated with This Genotype

Genotype
MGI:5790839

• Allelic Composition: Akap9^{tm1a(KOMP)Wtsi}/Akap9⁺
• Genetic Background: involves: C57BL/6 * C57BL/6N
• Cell Lines: EPD0033_5_D02

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:213427 )

decreased percent body fat/body weight ( J:213427 )

craniofacial

abnormal tooth morphology ( J:213427 )

growth/size/body

abnormal tooth morphology ( J:213427 )

decreased lean body mass ( J:213427 )

decreased body weight ( J:213427 )

hematopoietic system

decreased B cell number ( J:213427 )

decreased mature B cell number ( J:213427 )

increased T cell number ( J:213427 )

increased CD4-positive, alpha-beta T cell number ( J:213427 )

increased CD8-positive, alpha-beta T cell number ( J:213427 )

homeostasis/metabolism

decreased circulating glucose level ( J:213427 )

decreased circulating cholesterol level ( J:213427 )

decreased circulating HDL cholesterol level ( J:213427 )

decreased circulating LDL cholesterol level ( J:213427 )

increased circulating alkaline phosphatase level ( J:213427 )

decreased circulating serum albumin level ( J:213427 )

decreased circulating total protein level ( J:213427 )

increased energy expenditure ( J:213427 )

increased carbon dioxide production ( J:213427 )

increased oxygen consumption ( J:213427 )

immune system

decreased B cell number ( J:213427 )

decreased mature B cell number ( J:213427 )

increased T cell number ( J:213427 )

increased CD4-positive, alpha-beta T cell number ( J:213427 )

increased CD8-positive, alpha-beta T cell number ( J:213427 )

mortality/aging

lethality, incomplete penetrance ( J:213427 )

skeleton

abnormal tooth morphology ( J:213427 )

abnormal pelvic girdle bone morphology ( J:213427 )