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Phenotypes Associated with This Genotype
Genotype
MGI:5789297
Allelic
Composition		 Gdap1tm1Ics/Gdap1tm1Ics
Tg(Mpz-cre)26Mes/0
Genetic
Background		 involves: FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdap1tm1Ics mutation (0 available); any Gdap1 mutation (23 available)
Tg(Mpz-cre)26Mes mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
dysmyelination ( J:221297 )
• hypomyelination of the plantar nerve in 19 month old mice with no axonal loss

cellular
cellular phenotype ( J:221297 )
N
• axonal area covered by mitochondria in axons of plantar nerves is similar to wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory