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Phenotypes Associated with This Genotype
Genotype
MGI:5788485
Allelic
Composition		 Ddit3tm1Dron/Ddit3tm1Dron
Tg(Col2a1-rtTA,tetO-COMP*)2Jath/0
Genetic
Background		 involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddit3tm1Dron mutation (1 available); any Ddit3 mutation (19 available)
Tg(Col2a1-rtTA,tetO-COMP*)2Jath mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased inflammatory response ( J:233238 )
• doxycycline treated mice show decreased levels of inflammatory markers in the growth plate compared to Tg(Col2a1-rtTA,tetO-COMP*)2Jath/0 mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory