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Phenotypes Associated with This Genotype
Genotype
MGI:5788435
Allelic
Composition		 Tg(TNFSF11)5519Edou/0
Tnfsf11tles/Tnfsf11tles
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(TNFSF11)5519Edou mutation (0 available)
Tnfsf11tles mutation (2 available); any Tnfsf11 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:233240 )
• mice exhibit complete rescue of the abnormal phenotypes seen in single Tnfsf11tles homozygotes, including rescue of the osteopetrotic phenotype, of both lower and upper incisor eruption defects and of mesenteric lymph node organogenesis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory