Analysis Tools
homeostasis/metabolism
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• 78% reduction in alveolar fluid clearance as compared to controls
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respiratory system
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• lung permeability, wet-to-dry lung weight ratios and lung morphology are similar to controls
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• 78% reduction in alveolar fluid clearance as compared to controls
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• IEQ (equivalent short circuit current) is reduced in cultured alveolar epithelial cell monolayers as compared to controls, however, RT (transepithelial electrical resistance) is similar to controls
• cultured alveolar epithelial cell monolayers exhibit lower unidirectional Na+ flux in the apical-to-basolateral direction and unchanged Na+ flux in the basolateral-to-apical direction as compared to controls
• baseline net Na+ absorption is lower than in control monolayers
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